Zoloft

ZOLOFT® among other Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders.

Anyone considering the use of Zoloft or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality withantidepressants compared to placebo in adults beyond age 24; there was a reduction in riskwith antidepressants compared to placebo in adults aged 65 and older. Depression and certainother psychiatric disorders are themselves associated with increases in the risk of suicide.

Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescribers. Zoloft is not approved for use in pediatric patients except for patients with obsessive compulsive disorder (OCD).

(See Warnings: Clinical Worsening and Suicide Risk, Precautions: Information for Patients, and Precautions: Pediatric Use)

If you have any questions, please talk to your doctor.